Gene mutation helps predict lung cancer survival in nonsmokers - KFVS12 News & Weather Cape Girardeau, Carbondale, Poplar Bluff

Gene mutation may help predict lung cancer survival in nonsmokers

Updated: Sep 12, 2013 01:28 PM
© Stockbyte / Thinkstock © Stockbyte / Thinkstock
  • SPONSORED BY SOUTHEAST HEALTHMore>>

  • Quinn signs epinephrine law for Illinois schools

    Quinn signs epinephrine law for Illinois schools

    Wednesday, July 30 2014 6:36 PM EDT2014-07-30 22:36:36 GMT
    A new bill signed into Illinois law says trained personnel at schools statewide will be able to administer injectable epinephrine for those appearing to have strong allergic reactions.
    A new bill signed into Illinois law says trained personnel at schools statewide will be able to administer injectable epinephrine for those appearing to have strong allergic reactions.
  • Illinois Medicaid restricts use of hepatitis drug

    Illinois Medicaid restricts use of hepatitis drug

    Wednesday, July 30 2014 2:41 PM EDT2014-07-30 18:41:49 GMT
    Illinois is placing tight restrictions on a new hepatitis C drug that costs $1,000 per pill. Medicaid patients must meet 25 criteria and get prior approval before the government health care program will pay for...
    Illinois is placing tight restrictions on a new hepatitis C drug that costs $1,000 per pill. Medicaid patients must meet 25 criteria and get prior approval before the government health care program will pay for Sovaldi.
  • Surgeon general issues skin cancer warning

    Surgeon general issues skin cancer warning

    Wednesday, July 30 2014 11:04 AM EDT2014-07-30 15:04:38 GMT
    Nearly 5 million people are treated for skin cancer each year - more than cases of breast, prostate, lung and colon cancer combined.
    Nearly 5 million people are treated for skin cancer each year - more than cases of breast, prostate, lung and colon cancer combined.

THURSDAY, Sept. 12 (HealthDay News) -- Researchers say they've identified a gene mutation that's associated with a higher risk of lung cancer in women who do not smoke, but a better chance of survival in female and male lung cancer patients.

The mutation, which occurs in a gene that protects cells from oxidative stress, is found four times more often in women than in men, according to the study published Sept. 11 in the journal PLoS One.

The researchers analyzed the DNA of lung cancer patients in Japan and found that nonsmoking women with two copies of the -617A mutation in the NFR2 gene had a much higher incidence of lung cancer than nonsmoking men.

The investigators also found that both female and male lung cancer patients with this mutation had better survival rates than other patients.

This is the first study to provide clinical evidence that this mutation is associated with lung cancer patient survival, said researcher Dr. Toshihisa Ishikawa and colleagues at the RIKEN Center for Life Science Technologies in Japan.

The study strongly suggests that the presence of this mutation "is a good prognostic biomarker for the assessment of the overall survival chances of patients with adenocarcinoma, as well as a practical tool for personalized cancer therapy," Ishikawa said in a RIKEN news release.

Although the study found an association between the gene mutation and lung cancer survival, it did not prove a cause-and-effect relationship.

Lung cancer is the leading cause of cancer-related deaths in many industrialized countries, according to background information in the news release. Smoking is the main cause of lung cancer, but 10 percent to 15 percent of cases occur in nonsmokers.

More information

The U.S. National Cancer Institute has more about lung cancer.

Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
Powered by WorldNow

310 Broadway
Cape Girardeau, MO 63701

FCC Public File
publicfile@kfvs12.com
573-335-1212
EEO Report
Closed Captioning

All content © Copyright 2000 - 2014 Worldnow and KFVS12. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.